- Overview
- Product Description
- Product Details
- Application & Function
- Specification
Basic Info.
Product Description
| Product Name | Diltiazem |
| CAS No. | 42399-41-7 |
| MF | C22H26N2O4S |
| MW | 414.51784 |
| Appearance and shape | White or off-white crystalline powder |
Function
1.It is also used off-label as an effective preventive medication for migraine.
2.It is a class 3 antianginal drug, and a class IV antiarrhythmic.
3.Diltiazem hydrochloride is an antihypertensive and cardioprotective agent as well as a calcium channel protein inhibitor. It inhibits L-type Ca2+ channels and regulates Ca2+ release from intracellular stores in neutrophils.
Application
Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil, another nondihydropyridine (non-DHP) calcium channel blocker.
Chemically, it is based upon a 1,4-thiazepine ring making it a benzothiazepine-type calcium channel blocker.
