Basic Info.
Model NO.
FLZ-S0801tetracaine
Certification
GMP, HSE, ISO 9001, USP, BP
Suitable for
Elderly, Children, Adult
State
White Crystalline Powder
Purity
>99%
Appearance
White Cyrstalline Powder
CAS No
136-47-0
Shelf Life
2 Years
Test Method
HPLC
Storage
Store Cool Dry Place
Resource
Natural
Quality Requirement
Strictly Quality Control
Delivery Time
7-10days
MW
264.36300
Mf
C15h24n2o2
Transport Package
Foil Bag
Specification
99%
Trademark
Xi′an Frazer Biotech Co., Ltd.
Origin
China
Production Capacity
2500kg/Month
Product Description
Pharmaceutical Raw Powder Tetracaine Hydrochloride Powder CAS NO. 136-47-0
Specification
| Test Items | Specification | Test Results |
| Appearance | white crystalline powder | confirm |
| Identification | ABC in Pass | confirm |
| Solubility | Very soluble in water, soluble in Alcohol; insoluble in Ether and Benzene | confirm |
| USP Reference standards | USP Tetracaine Hydrochloride RS,USP Endotoxin RS. | confirm |
| Melting point | 145~150 degree | 146.0~147.5 degree |
| Chromatographic purity | In Pass | confirm |
| Related substance | Not more than the reference solution 0.05% | confirm |
| Heavy metals | ≤10ppm | confirm |
| PH | 4.5-6.5 | 5.8 |
| Residue on ignition | ≤0.10% | 0.05% |
| Loss on Drying | ≤ 0.5% | 0.19% |
| Assay | 98.0 -101.0% | 100.1% |
What is Tetracaine ?
Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount
Function and Application of Tetracaine
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
